Toothache, Tooth Bleaching
Conditions
Brief summary
This study aims to evaluate the effects of prior use of non-steroidal anti-inflammatory Naproxen on risk and level of tooth sensitivity caused by in-office bleaching procedures.
Interventions
DRUGNaproxen
The patient will receive a single-dose of Naproxen (500 mg) one hour before the bleaching procedure.
Sponsors
Universidade Federal de Sergipe
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* At least 18 years old patients of both genders presenting good general/oral health; * All maxillary anterior teeth presenting shade equal or darker than 2M2 at Vita bleachguide guide (Vita-Zahnfabrik, Germany); * Signed the form accepting to participate of this study.
Exclusion criteria
* Presence of caries lesions, restorations and/or endodontic treatment at any maxillary anterior teeth. * Undergone tooth-whitening procedures; * Pregnant/lactating; * Presence of periodontal diseases; * Presence of severe tooth discoloration by tetracycline stains or fluorosis; * Any kind of medicine, bruxism habits or any other pathology that can cause sensitivity (such as recession, dentin exposure); * Continuous use of drugs with anti-inflammatory actions; * Presence of tooth hypersensitivity at baseline measurement; * Any known adverse effects caused by Naproxen; * Non-attendance to any session of evaluation or bleaching.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Risk to Tooth sensitivity - during procedure | During the bleaching procedure | The tooth sensitivity will be evaluated using a 5-point Verbal rating scale (VRS), where 0 = none, 1 = mild, 2 = moderate, 3 = considerable and 4 = severe. Score different from 0 will determine presence of sensitivity. The risk of tooth sensitivity will be determined by relative risk assessed by ratio between absolute risk of experimental condition by those observed in control. The 95% confidence interval will be calculated. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Level of tooth sensitivity - during procedure | During the bleaching procedure | The tooth sensitivity will be evaluated using a 5-point Verbal rating scale (VRS), where 0 = none, 1 = mild, 2 = moderate, 3 = considerable and 4 = severe. |
| Risk of tooth sensitivity - after procedure | 24 hours after bleaching prcedure | The tooth sensitivity will be evaluated using a 5-point Verbal rating scale (VRS), where 0 = none, 1 = mild, 2 = moderate, 3 = considerable and 4 = severe. Score different from 0 will determine presence of sensitivity. The risk of tooth sensitivity will be determined by relative risk assessed by ratio between absolute risk of experimental condition by those observed in control. The 95% confidence interval will be calculated. |
| Level of tooth sensitivity - after procedure | 24 hours after bleaching prcedure | The tooth sensitivity will be evaluated using a 5-point Verbal rating scale (VRS), where 0 = none, 1 = mild, 2 = moderate, 3 = considerable and 4 = severe. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Efficacy of bleaching | 7 days after bleaching procedure | A spectrophotometer will be used to assess the color alteration, while the parameter L, a and b will be recorded. |
Countries
Brazil
Outcome results
None listed