Pediatric Obesity, Sleep Apnea, Obstructive
Conditions
Keywords
Sleep Apnea, Obstructive, Pediatric Obesity
Brief summary
The prevalence of childhood obesity has increased at an alarming rate over the last decades, both globally and in Denmark. There are a number of serious sequelae related to obesity, such as hypertension, hypercholesterolemia, fatty liver and prediabetes. Obesity is found to be a risk factor for obstructive sleep apnea (OSA). OSA in childhood is known to be associated with cardiovascular complications, neurocognitive problems and reduced quality of life. The correlation between obesity and OSA is still poorly understood. Early detection and intervention is of great importance as the health consequences related to OSA as well as obesity are severe. Adenotonsillectomy is recommended as first-line therapy in children with OSA. However, only around 25% of obese children benefit from this treatment compared to around 75% of normal-weight children suggesting that there might be other structural factors predisposing to OSA in obese children. In this study the investigators aim to clarify the impact of obesity in the development of OSA. The prevalence of OSA in obese children will be investigated. Furthermore the purpose is to assess the effect of weight loss on OSA.
Interventions
BEHAVIORALWeight loss
Sponsors
Holbaek Sygehus
Zealand University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
7 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* Age: 7-18 years * BMI \> 90th percentile for age and gender
Exclusion criteria
* Neuromuscular disorders * Craniofacial syndromes / malformations * Laryngeal and tracheal malformations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in obstructive sleep apnea (OSA) | One year | OSA will be diagnosed by cardiorespiratory measurement. The examination will be repeated after weight loss. |
Countries
Denmark
Outcome results
None listed