Risk Analysis for Cardiovascular Autonomic Neuropathy

The Risk Analysis for Cardiovascular Autonomic Neuropathy in General Chinese Population

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02462616

Enrollment

2100

Registered

2015-06-04

Start date

2011-01-31

Completion date

2016-12-31

Last updated

2017-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Autonomic Neuropathy

Keywords

risk analysis, general Chinese population, cardiovascular autonomic neuropathy

Brief summary

This is a large-scale, community-based, cross-sectional study to evaluate environmental and genetic risk factors for cardiovascular autonomic neuropathy in general Chinese population.

Detailed description

A large-scale, community-based, cross-sectional study was conducted to explore the extent to which risk factors associated with cardiovascular autonomic neuropathy (CAN) in general Chinese population. A total of more than 2000 participants were recruited by using multiple stages sampling (first cluster sampling and then simply sampling). Data involved in demographic information, clinical biomarkers such as glucose and lipids profiles, medical and therapy history were collected. Every participants was complete DNA extracted and genotyped. Cardiovascular autonomic functions were measured by using short-term heart rate variability (HRV) to evaluate the outcome of CAN. Univariate and multiple variables analysis have been performed to examine potential environmental and genetic risk factors of CAN. In addition, clinical risk model, simply screening model and non-linear system model such as artificial neural network was created, respectively.

Interventions

OTHERnot intervention

This is a cross-sectional study, no intervention was performed.

Study design

Observational model

ECOLOGIC_OR_COMMUNITY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

30 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* Survey Chinese participants with undiagnosed CAN * Aged 30-90 years, were included in this study.

Exclusion criteria

* Some subjects were excluded from the study to eliminate potential confounding factors that may have influenced their CA function. Briefly, the

Design outcomes

Primary

Measure	Time frame
cardiovascular autonomic neuropathy (CAN) measured by short-term heart rate variability (HRV)	participants will be measured for the duration of outpatient stay, an expected average of 2 weeks

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026