Elastography, Thyroid Nodule
Conditions
Keywords
Elastography, Thyroid nodule
Brief summary
For patients with thyroid gland nodule, fine-needle aspiration biopsy has been proved to be an efficient tool for thyroid cancer diagnosis. However, it is somewhat an invasive procedure and is subject to sampling and analysis uncertainties. Thus, improved, more reliable criteria for determining which nodule should be be aspirated are needed. Ultrasound elastography has been shown to be useful in the differential diagnosis of breast and prostate cancers. Ultrasound elastography also may discriminate malignant from benign nodule.
Detailed description
To prospectively evaluate the elastographic appearance of thyroid cancer and explore the potential sensitivity and specificity of elastography for differentiating benign and malignant tumors, with histopathologic analysis as the reference standard.
Interventions
None listed
Sponsors
Dong Jun Lim
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- The patients with thyroid nodule who are supposed to take fine needle aspiration biopsy
Exclusion criteria
\- The patients who do not want to participate in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic performance of elastography using in-vivo compression for detection of thyroid cancer | 1 year | Measuring ECI(Elasticity contrast index) of thyroid nodule by ultrasound elastography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Determination of the parameters which could have influence on the diagnostic performance of ultrasound elastography using in-vivo compression | One year | Analysis of clinical characteristics of thyroid nodules and patients which are related to the diagnostic performance of ultrasound elastography |
Countries
South Korea
Contacts
Primary ContactDong Jun Lim, Dr.
Backup ContactKwanhoon Jo, Dr.
Outcome results
None listed