Diabetic Cardiovascular Autonomic Neuropathy (DCAN)
Conditions
Keywords
Bayesian estimation, short-term heart rate variability, diabetic cardiovascular autonomic neuropathy, diagnostic performance, Diagnostic performance, short-term heart rate variability, diabetic cardiovascular autonomic neuropathy, DCAN
Brief summary
This study aimed to estimate sensitivities and specificities of diabetic cardiovascular autonomic neuropathy (DCAN) diagnostic tests using the Bayesian approach without a gold standard in another independence dataset.The reference the values for the short-term HRV were calculated in the investigators' previous study (including 371 healthy subjects). This study dataset contained 200 diabetic patients who completed both the short-term HRV test and Ewing's test. Simultaneous inferences about the population prevalence and the performance of each diagnostic test were possible using the Bayesian approach without a gold standard.
Detailed description
The CAN prevalence is rapidly growing in all populations worldwide. No document has been reported diagnostic performance of short-term heart rate variability (HRV) for diabetic cardiovascular autonomic neuropathy (DCAN) in the Chinese population. This study aimed to estimate sensitivities and specificities of DCAN diagnostic tests using the Bayesian approach, in the absence of a gold standard in another independence dataset.The reference the values for the short-term HRV were calculated in the investigators' previous study (including 371 healthy subjects). This study dataset contained 200 subjects who completed both the short-term HRV test and Ewing's test. Simultaneous inferences about the population prevalence and the performance of each diagnostic test were possible using the Bayesian approach without a gold standard.
Interventions
OTHERnot intervention
This is a cross-sectional study for estimation of diagnostic performance.
Sponsors
Shanghai Tongji Hospital, Tongji University School of Medicine
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
30 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* Survey diabetic participants with undiagnosed CAN, aged 30-90 years, were included in this study.
Exclusion criteria
* Some subjects were excluded from the study to eliminate potential confounding factors that may have influenced their CA function. Briefly, the
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diabetic cardiovascular autonomic function evaluate by short-term heart rate variability test | participants will be measured for the duration of outpatient stay, an expected average of two days | Both short-term heart rate variability and Ewing's test measure diabetic cardiovascular autonomic function |
| Diabetic cardiovascular autonomic function evaluate by Ewing's test | participants will be measured for the duration of outpatient stay, an expected average of two days | Both short-term heart rate variability and Ewing's test measure cardiovascular autonomic function |
Countries
China
Outcome results
None listed