Dentin Sensitivity, Periodontal Diseases
Conditions
Keywords
Dentin hypersensitivity, Periodontal disease, Arginine
Brief summary
This study aim is to determine the efficacy of two Oral Hygiene Regimens in the reduction of dentin hypersensitivity on subjects undergoing non-surgical periodontal treatment, over a period of 8 weeks.
Detailed description
This study aim was to determine the efficacy of two Oral Hygiene Regimens in the reduction of dentin hypersensitivity on subjects undergoing non-surgical periodontal treatment, over a period of 8 weeks. The study was conducted in Piracicaba Dental School, Piracicaba, São Paulo, Brazil, using a double-blind/two treatment design. Sixty subjects (30 per group) that meet the inclusion and exclusion criteria were assigned to the groups: Test group (Non-surgical periodontal treatment + In-office application of Colgate Sensitive Pro-Relief - CSPR + tooth brushing with at home CSPR toothpaste) and Control group (Non-surgical periodontal treatment + In-office application of a fluoride-free prophy paste + tooth brushing with a Colgate Cavity Protection Toothpaste). Air blast sensitivity assessments were used to compare the efficacy of the two approaches using both the Schiff scale. The sensitivity parameters were measured at baseline, 1, 4 and 8 weeks.
Interventions
DRUGIn-office and at home Colgate sensitive pro-relief - CSPR
Prophylaxis with rubber cup using In-office Colgate sensitive pro-relief (CSPR), after non-surgical periodontal therapy, and tooth brushing with at home CSPR toothpaste.
DRUGIn-office Villevie® prophy paste + Colgate Toothpaste
Prophylaxis with rubber cup using In-office Villevie® (fluoride-free) prophy paste + Colgate Toothpaste, after non-surgical periodontal therapy.
PROCEDURENon-surgical periodontal treatment
Full-mouth debridment, scaling and root planing with ultrasonic/hand instruments
Sponsors
Colgate Palmolive
University of Campinas, Brazil
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
30 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. Males and females, between 30-75 years of age; 2. Availability for the duration of the study; 3. Individuals diagnosed with moderate chronic periodontal disease (4-5 mm loss of clinical attachment, according to AAP), and indication for non-surgical periodontal therapy; 4. Diagnosis, by air blast, of at least two (2) hypersensitive teeth with a score of 2 or 3 on the Schiff Cold Air Sensitivity Scale; 5. Subjects in good general health and no allergies to products that are being tested.
Exclusion criteria
1. Oral pathology, chronic disease, or a history of allergy to testing products; 2. Qualifying sensitive teeth with extensive/defective restorations, pulpitis, caries, cracked enamel, or these teeth used as abutments for removable partial dentures; 3. Subject using anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory medication or daily analgesics within one month prior to the start of the study or scheduled to start such intake during the course of the study; 4. Subject regularly using desensitizing toothpaste; 5. Current smokers; 6. Subject pregnant or breast feeding; 7. Allergies to oral care products, personal care consumer products, or their ingredients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dentin hypersensitivity reduction | Baseline, 8 weeks | Air blast sensitivity assessments using Schiff scale at baseline and up to 8 weeks after non-surgical periodontal treatment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Probing depth reduction | Baseline, 8 weeks | Full-mouth probing, at baseline and up to 8 weeks after non-surgical periodontal treatment. |
Countries
Brazil
Outcome results
None listed