Topical Lidocaine After Arthroscopy on Knee

Postoperative Pain Management With Topical Lidocaine After Arthroscopy on Knee. A Randomized Double-blind Study

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02460627

Enrollment

180

Registered

2015-06-02

Start date

2015-05-31

Completion date

2017-01-31

Last updated

2015-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain, Topical Anaesthesia

Keywords

Arthroscopy, Meniscus, Lidocaine

Brief summary

More than half of the patients suffer from intensive pain 1-2 days after arthroscopy in the knee. Walking function and physical activities are affected by this intensive pain although local anaesthetic is given in the joint and soft tissue. The patients are often discharged on the same day as the arthroscopy takes place depending on their ability to walk with or without assistive technology. It is a well-known fact that the patient is given a dose of morphine, analgesics or an ice pack on a painful knee to reduce pain intensity. The aim of the project is to study whether pain intensity and analgesics can be additionally reduced by giving local anaesthetic by means of an adhesive tape placed on the skin instead of giving morphine, analgesics or ice pack on a painful knee. The researchers plan to include a cohort of 180 patients: 60 patients having a meniscus sutured, 60 patients having meniscus tissue removed surgically, 60 patients having mucous fold removed surgically. This study is planned to be a pilot study in order to complete a future large medical science study.

Interventions

DRUGLidocaine adhesive tape

700 mg for 12 hours

OTHERAdhesive tape

For 12 hours

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Planned resection of meniscus (DS832, DM232) * Planned meniscus suture (DS832) * Planned plica resection (DM659) * Patients \>=18 years and \<50 years * Statement of consent * Tolerance to Lidocaine (analgesics)

Exclusion criteria

* Type 1 diabetes or type 2 diabetes * Allergic to Lidocaine (analgesics) * Heart disease, liver disease, kidney disease * BMI \>=35 * Unability to read or speak Danish * Rheumatoid arthritis or other degenerative diseases in joint, bone structure or cartilage * Insufficient coagulation * Medication of morphine pre-operatively * Pregnant and nursing women

Design outcomes

Primary

Measure	Time frame	Description
Administration of analgesics or morphine in time	1 day	First time administration of analgesics or morphine in time on demand

Secondary

Measure	Time frame	Description
Discharges of patients in time	1 day	—
Value Added Score (VAS) estimation of pain	1 day	Estimate pain at each administration of analgesics on demand before discharge of patients.

Countries

Denmark

Contacts

Primary ContactSten Rasmussen, M.D.

sten.rasmussen@rn.dk25520462

Backup ContactSofie S. Lang

s.lang@rn.dk

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026