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Modeling and Testing Change in Mental Abilities in Childhood

Modeling and Testing Change in Mental Abilities in Childhood Through Computer-based Interventions

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02459873
Enrollment
20
Registered
2015-06-02
Start date
2015-06-30
Completion date
2016-08-31
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low Executive Function in Children

Brief summary

Children with low executive function, working memory and attention skills in childhood not only do poorly at school, but also go on to do poorly on social, health, and financial indicators in adulthood. The rate of executive function disorders in children is vastly underestimated at 17% , even when taking into account two of the more widely known disorders of Attention Deficit Hyperactivity Disorder (11%) and Fetal Alcohol Spectrum Disorders (6%), but children of lower socioeconomic status are especially vulnerable due to reduced resource availability. As executive function, working memory and attention skills are central to success in later life, if children with low skills can be given targeted training to improve the skills they fall short on, there is potential to both improve their short-term academic performance, and influence long-term achievement. In fact, poor executive function skills and poor attention and working memory is a large predictor of poor performance even in typically developing children who are doing poorly academically. Hypothesis 1. Those with lower working memory will also have lower problem solving skills and lower indices of other executive functioning skills such as reasoning/problem solving. Hypothesis 2. Children that start with lower WM and PS will show the highest gains in training related performance, and such high gains on WM and PS will lead to better performance post-intervention compared to baseline measures of cognitive function. Hypothesis 3: Those who make the largest gains in WM and PS with training will show more retention of training gains at 6 months compared those who show lower gains. Aim 1. Assess working memory (WM) and processing speed (PS) skills in children and their inter-relationships with executive functioning skills Aim 2. Examine change in cognitive function in WM and PS after intensive training in WM and PS, during and immediately post-intervention Aim 3. Examine long-term retention of training effects on WM, PS, and executive functions. The purpose of this study is to establish an effective and targeted working memory and processing speed intervention in children ages 7-10 with low to average executive function skills, by utilizing home-based computer games specifically designed to appeal to children. Following institution approved consents, 60 low socioeconomic status children from Los Angeles will be recruited and enrolled in the study and be asked to play specific fun, but targeted cognitive computer games for 10 weeks. The results of this pilot study will establish a protocol for feasibility of improving executive function skills in children with underdeveloped skills and inform on sufficiency of sample sizes, length of interventions, and directly impact computer-based intervention research and cost-effective techniques in children's cognitive development within the next 3-5 years.

Interventions

BEHAVIORALComputer games to assess change in executive function skills

Children get access to computer games for 10 weeks for an hour each week.

Sponsors

University of Southern California
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
84 Months to 132 Months
Healthy volunteers
Yes

Inclusion criteria

* Understands and speaks English

Exclusion criteria

* Diagnosed psychological disorder * Head trauma with loss of consciousness of \>5 minutes

Design outcomes

Primary

MeasureTime frameDescription
Change in working memory skills assessed through Executive Function Battery and NIH ToolBox3 monthsChildren will be assessed both on Executive Function Battery and the NIH Toolbox battery to examine change in working memory skills.
Change in processing speed skills assessed through Executive Function Battery and NIH ToolBox3 monthsChildren will be assessed both on Executive Function Battery and the NIH Toolbox battery to examine change in processing speed skills.

Secondary

MeasureTime frameDescription
Change in school grades in science, reading and math.3-6 monthsParents will be asked for children's school grades at the beginning of the study, during the study, and at the end of the study to assess the effects of the intervention
Change in parent reported behavior as assessed through BRIEF and CBCL questionnaires3-6 monthsParental reports on BRIEF (Behavior Rating Inventory of Executive Function) and CBCL (Child Behavior Checklist) questionnaires will be used to assess change in behavior

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026