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Inspiratory Muscle Training and Hospital Complications

Safety and Efficacy of Inspiratory Muscle Training for Preventing Adverse Outcomes in Patients at Risk of Prolonged Hospitalization

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02459444
Acronym
IMT
Enrollment
54
Registered
2015-06-02
Start date
2015-05-31
Completion date
2016-08-31
Last updated
2017-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Weakness

Keywords

Respiratory Muscles, Muscle Weakness, Hospitalization, Length of Stay, Mortality

Brief summary

The inspiratory muscle training (IMT) is a feasible and safe strategy for patients and athletes, your goal is to recondition the respiratory muscles, providing optimization of lung capacity, either for high performance sport as to support metabolic wear caused by illness. It is generally agreed the positive impact of the application of a TMI Protocol on maximal inspiratory pressure (MIP), this benefit encourages individuals sick since weaning from mechanical ventilation (MV), to the optimization of physical performance in cardiac and / or pulmonary rehabilitation. The TMI is based on the principles: the burden imposed on the muscle; the specificity of training; the reversibility of the gain and muscle atrophy.

Detailed description

This prospective double-blind (patient and evaluator) randomised controlled trial compared the efficacy of inspiratory muscle training and inspiratory muscle training. The study protocol for this trial was described elsewhere. This study was conducted in accordance with Consolidated Standards of Reporting Trials recommendations. The trial was performed at the Roberto Santos General Hospital in Salvador, Bahia, Brazil. This study was approved by the institutional hospital ethics committee (approval reference number 03/2014). Before enrolment, written informed consent was obtained from participants or their legal guardians.

Interventions

Respiratory equipment for physiotherapy, offering to load muscles inspiratory

OTHERPhysiotherapy

This was contemplated cinesioterapia unloaded, muscle stretching, coughing technique, sedestração and ambulation if the participant was fit.

Sponsors

Federal University of Bahia
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Admission to the hospital ward; * At least two of the following risk factors for prolonged hospitalization: two or more comorbidities; sepsis; liver, lung, or kidney diseases; neoplasia; mechanical ventilation; and use of vasopressor or dialysis therapy.

Exclusion criteria

* Patients with a cognitive disability that made them unable to perform the respiratory training; * Uncontrolled cardiac arrhythmias; * Circulatory shock; * Acute ischemic heart disease; * acute respiratory failure (characterised by a partial pressure of arterial oxygen \< 60 mmHg or a partial pressure of arterial carbon dioxide \> 50 mmHg); * neuromuscular disease or myopathies; * diaphragmatic paresis or paralysis were excluded from the protocol.

Design outcomes

Primary

MeasureTime frameDescription
hospital inpatient complicationsDischarge from hospitalFollow-up during hospitalization

Secondary

MeasureTime frameDescription
respiratory muscle strengthAfter 4 weeks followMeasured with manometer for 3 reps.

Other

MeasureTime frameDescription
peripheral strengthfour weeksMedical Research Council score
Functional Independence Measure questionnaireDischarge from hospitalIdentifies said functional capacity
Index of BarthelDischarge from hospitalIdentifies said functional capacity

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 8, 2026