Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02458573

Enrollment

Registered

2015-06-01

Start date

2015-06-04

Completion date

2016-03-28

Last updated

2017-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer

Brief summary

The investigators hypothesized that sympatholytic effect of epidural analgesia would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to compare the effect of epidural analgesia and intravenous analgesia on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.

Interventions

OTHERcontinuous epidural analgesia

the continuous epidural analgesia group: epidural analgesia started from induction of anesthesia and continued for 48 h.

OTHERcontinuous intravenous analgesia

the continuous intravenous analgesia group: intravenous analgesia started from induction of anesthesia and continued for 48 h.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* patient between 20 and 70 of age with ASA physical status Ⅰ-Ⅲ * gastric cancer patient undergoing laparoscopic gastrectomy

Exclusion criteria

* ASA physical status Ⅳ * bradycardia (\< 60 bpm), arrhythmia * uncompensated heart failure * hepatic failure (Child-Pugh score B) * renal failure (eGFR MDRD \< 60 ml/min/1.73m2)

Design outcomes

Primary

Measure	Time frame	Description
the time to first gas passing after surgery	within 5days after surgery	Outcome will be assessed by a investigator blinded to the study group.
the time to resume water intake after surgery	within 5days after surgery	Outcome will be assessed by a investigator blinded to the study group.
soft diet intake after surgery	within 5days after surgery	Outcome will be assessed by a investigator blinded to the study group.

Secondary

Measure	Time frame	Description
postoperative pain	immediately after surgery to 48 hours	numerical rating scale 0 (no pain) to 10 (worst pain)

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026