Cardiac Surgical Procedures, Thoracic Surgical Procedures, Sternotomy
Conditions
Brief summary
Pulse pressure variation (PPV) is a well-known dynamic preload indicator to predict fluid responsiveness. However, its usefulness in open-chest conditions has been equivocal. The investigators evaluated whether PPV measured during Valsalva maneuver can predict fluid responsiveness after sternotomy.
Interventions
PROCEDUREValsalva maneuver
Valsalva maneuver was performed after sternotomy with the constant airway pressure of 30cmH2O for 2 breaths duration.
OTHERFluid loading
We record the cardiac index values before and after volume expansion with 6ml/kg of balanced crystalloid
Sponsors
Samsung Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
\- Adult patients undergoing elective off-pump coronary arterial bypass grafting
Exclusion criteria
* Preoperative LV EF \<= 35% * Moderate or severe valvular heart disease * Cardiac arrhythmia * Intracardiac shunt * Severe renal or liver disease * Moderate to severe pulmonary hypertension (mean PAP \> 35 mmHg) * Patients with bullous lung disease or combined pneumothorax
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulse pressure variation during Valsalva maneuver | during Valsalva maneuver |
Secondary
| Measure | Time frame |
|---|---|
| Pulse pressure variation after sternotomy | 5 min after sternotomy |
Countries
South Korea
Outcome results
None listed