Cerebral Palsy
Conditions
Keywords
Sensor Fusion, Stochastic Resonance Stimulation, Sensory deficits, Postural Control
Brief summary
The purpose of this study is to investigate how sensory information processing affects balance ability in children with cerebral palsy (CP). An additional goal is to determine if a subsensory electrical stimulation called Stochastic Resonance (SR) Stimulation, can improve balance in children with CP. Children with CP and children with typical development will participate and complete a series of clinical and balance assessments. They will also be tested in a sensor fusion paradigm to investigate potential deficits in the dynamic integration of visual, vestibular and proprioceptive information during upright stance. SR stimulation will then be used to potentially improve these deficits and subsequently their balance ability.
Interventions
PROCEDURESensory Integration Testing
Investigate how sensory information are integrated during upright stance when visual and body senses are challenged in a virtual reality environment
PROCEDURESR stimulation & Sensory integration testing
Use SR stimulation to improve sensory integration when visual and body senses are challenged in a virtual reality environment
Sponsors
Shriners Hospitals for Children
University of Delaware
Temple University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
8 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
* Diagnosis of spastic diplegia CP (GMFCS I- III)\* * Ability to stand independently for approximately 2 min
Exclusion criteria
* Lower extremity surgery or fractures in the year prior testing * Joint instability or dislocation in the lower extremities * Botulinum toxin injections in the lower extremities within the past 6 months\* * Marked visual or hearing deficits * Uncontrolled seizure disorder * Implanted medical device that may be contraindicated with application of SR stimulation * Asterisk indicates the eligibility criteria that should be met only by children with CP
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gain response | 1 day | For both the sensory reweighting testing, the visual signal will be displayed as a visual flow with translation in anterior-posterior (AP) direction (i.e., sagittal plane) and presented at different amplitudes (0.25 and 0.5 cm) at 0.2 Hz to measure: the change in gain (weighting) to vision (intramodal effect); and a change in gain to vibration and galvanic stimulation (intermodal effects). Gain for each modality relative to both the leg segment AP translation and trunk segment AP translation will be measured. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Gain response | 1 day | For the sensory reweighting with the addition of SR stimulation testing, the visual signal will be displayed as a visual flow with translation in anterior-posterior (AP) direction (i.e., sagittal plane) and presented at different amplitudes (0.25 and 0.5 cm) at 0.2 Hz to measure: the change in gain (weighting) to vision (intramodal effect); and a change in gain to vibration and galvanic stimulation (intermodal effects). Gain for each modality relative to both the leg segment AP translation and trunk segment AP translation will be measured. |
Countries
United States
Contacts
Primary ContactAnastasia Zarkou, PT, MS
Backup ContactSamuel CK Lee, PT, PhD
Outcome results
None listed