Esophageal Cancer
Conditions
Keywords
Acute toxicity, Late toxicity, Prediction models
Brief summary
Motive: In order to improve the treatment technique, a comprehensive follow-up program is needed to obtain all relevant patient, treatment and toxicity data from esophageal cancer patients. Goal: To set-up and maintain a database containing treatment results in terms of tumor control, side effects, complications and patient-reported quality of life. A standard database of patients receiving photon treatment will be created. These data are then linked to dose-volume data of radiotherapy, with the aim to build prediction models for both tumor control and toxicity after radio (chemo) therapy that can later be used for selecting patients for proton treatment.
Interventions
RADIATIONRadiotherapy
Sponsors
University Medical Center Groningen
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with esophageal cancer * Patients receiving a radiotherapy dose \> 40 Gy
Exclusion criteria
* Failure to comply with any of the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute toxicity | Highest during and within 2 weeks after last day of radiation therapy |
| Late toxicity | Highest within one year after last day of radiation therapy |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival | At 1,2,3,4 and 5 years after first day of radiation therapy |
| Loco-regional tumor control | At 1,2,3,4 and 5 years after first day of radiation therapy |
Other
| Measure | Time frame |
|---|---|
| Patient-rated symptoms and Quality-of-Life | Before first day of radiation therapy and at 3,6,12,24,36,48,60 months after first day of radiation therapy |
Countries
Netherlands
Contacts
Primary ContactCT Muijs, MD PhD
Outcome results
None listed