Brain Concussion
Conditions
Keywords
Injury, Brain, Traumatic Mild, Mild Traumatic Brain Injury
Brief summary
Evaluation of the utility of a multi-modal assessment tool in distinguishing between individuals with and without a history of mild traumatic brain injury.
Detailed description
This was a preliminary validational study of a multi-modal concussion assessment battery incorporating eye-tracking, balance, and neurocognitive tests on a new hardware platform, the Computerized Brain Injury Assessment System (CBIAS). Using receiver operator curve (ROC) analyses, 1) a subset of the most discriminating neuro-physiological assessment tests involving smooth pursuit eye motion (SPEM) tracking errors, corrective saccade counts, a balance score ratio sensitive to vestibular balance performance and two neurocognitive tests of response speed and memory/incidental learning, was identified, 2) the enhancement in discriminatory capability of detecting concussion-related deficits through the combination of the identified subset of assessments was demonstrated, and 3) the effectiveness of a robust and readily implemented global scoring approach was demonstrated for both eye track and balance assessment tests. These results are significant in introducing a comprehensive solution for concussion assessment that incorporates an economical, compact and mobile hardware system and an assessment battery that is multi-modal, time efficient and whose efficacy has been demonstrated on a preliminary basis. This represents a significant step toward the goal of a system capable of making a dependable return-to-play/duty determination based on concussion likelihood.
Interventions
Subjects were assessed using a multi-modal concussion assessment battery incorporating eye-tracking, balance, and neurocognitive tests
Sponsors
Study design
Eligibility
Inclusion criteria
* Military personnel * Age 18 to 45 * Diagnosis of mTBI within past 5 years * Rancho Los Amigos Scale score of 7 or above
Exclusion criteria
* Non-military individuals * Below age 18 or older than 45 * No diagnosis of mTBI within past 5 years * Rancho Los Amigos Scale score of 6 or below
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Receiver-operator-curve area under the curve (AUC) | up to 5 years | Each test's discrimination capability was quantified using AUC and p value |