Osteoporosis of Disuse With Current Pathological Fracture
Conditions
Brief summary
A large-scale, community-based, cross-sectional study was conducted to evaluate the extent to which lifestyle was associated with osteoporosis among the Chinese population by using self-reported questionnaire methods.
Detailed description
A large-scale, community-based, cross-sectional study was conducted to evaluate the extent to which lifestyle was associated with osteoporosis among the Chinese population by using self-reported questionnaire methods. More than 3000 participants were recruited in communities in Shanghai. Data involved in demographic information, lifestyle, dietary habits, medical history and clinical biomarkers were collected. Every participants were measured bone mineral density (BMD g/cm2) at calcaneus by standardized quantitative ultrasound (QUS, Hologic Inc., Bedford, MA, USA) utilizing T-scores based on WHO criteria. A standard statistical analysis including univariate and multiple variables regression analysis to explore the risk or preventive factors involved in Chinese lifestyle associated with osteoporosis.
Interventions
None listed
Sponsors
Huashan Hospital
Shanghai Tongji Hospital, Tongji University School of Medicine
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
30 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* Participants aged 30-90 years were recruited from rural and urban communities in Shanghai.
Exclusion criteria
* Some participants with chronic diseases and conditions that might potentially affect bone mass, structure, or metabolism were excluded. Briefly, the
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| osteoporosis accessed by Bone Mass Density (BMD) | participants will be measured for the duration of outpatient stay, an expected average of 2 weeks | The bone mineral density (BMD g/cm2) was measured at calcaneus by standardized quantitative ultrasound (QUS, Hologic Inc., Bedford, MA, USA) utilizing T-scores based on WHO criteria, which were obtained from the automated equipment. T-score refers to the ratio between patient's BMD and that of young adult population of same sex and ethnicity. T-score of \> -1 was taken as normal, between -1 and -2.5 osteopenic and \< -2.5 as osteoporotic. |
Countries
China
Outcome results
None listed