Effects of High Altitude
Conditions
Keywords
healthy volunteers, acclimatization, sleep, hypoxia
Brief summary
The study evaluates respiratory acclimatization in healthy lowlanders staying for 3 weeks at 3200 m.
Detailed description
This study evaluates the effect of 3 weeks altitude acclimatization on sleep related breathing disturbances in healthy subjects staying at 3200 m. Participants living in Bishkek, Kyrgyzstan (700 m), will be transferred by car within 4 h to the Tuja Ashu high altitude clinic (3200 m). Outcomes will be assessed repeatedly during the stay at 3200 m.
Interventions
Participants will stay for 3 weeks at an altitude of 3200 m
Sponsors
Study design
Eligibility
Inclusion criteria
* Perfect health * Born, raised and currently living at low altitude (\<800m) * Informed consent.
Exclusion criteria
* Any acute or chronic disease * heavy smoking (\>20 cigarettes per day).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean nocturnal oxygen saturation measured by pulse oximetry | night 7 at 3200 m | Difference in mean nocturnal oxygen saturation between night 1 and night 7 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mean nocturnal oxygen saturation measured by pulse oximetry | night 1 at 3200 m | Difference in mean nocturnal oxygen saturation between night 1 at 3200 and night 1 at 700 m |
Countries
Kyrgyzstan