Postoperative Pain
Conditions
Keywords
Requirement of postoperative pain medication
Brief summary
Continuous ropivacaine infusion to sternotomy wound after coronary artery bypass grafting (CABG) or heart valve surgery to diminish postoperative pain.
Detailed description
A multiporous catheter will be introduced into sternotomy wound to CABG or heart valve surgery patients and continuous ropivacaine infusion 4 ml/h will be started immediately after surgery. Ropivacaine infusion will be administered during 48 postoperative hours. All patients receive patient controlled analgesia (PCA) oxycodone after extubation in the PACU. All patients receive a standardized anesthesia during surgery.
Interventions
DRUGRopivacaine
Sponsors
Kuopio University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Elective CABG or heart valve surgery patients
Exclusion criteria
* Psychic disorders * Sleep apnea syndrome * Diabetes mellitus (insulin dependent) * Obesity, body mass index (BMI) ≥ 35 * Cardiac insufficiency, ejection fraction (EF) ≤ 30
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative oxycodone consumption | 48 postoperative hours | postoperative PCA administered oxycodone |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain measured with Visual Analog Scale | 48 postoperative hours | pain measured with VAS at rest and on movement |
Countries
Finland
Outcome results
None listed