Coronary Artery Disease, Diabetes, Heart Failure, Hypertension, Lifestyle, Smoking
Conditions
Keywords
hypertension, epidemiology, glucose, body mass index, lipids, smoking, coronary artery disease, arterial stiffness, carotid ultrasound
Brief summary
The study addresses epidemiology of cardiovascular risk factors and major cardiovascular diseases in Russian Federation (urban and rural population). 12 regions of 1600 participants in each will be included.
Detailed description
Plasma lipids and fasting glucose, heart rate and blood pressure, anthropometry, smoking and alcohol questionaries, nutrition, sleep quality, stress will be assessed. ECG records are obtained form all participants. Subclinical target organ damage (carotid and periferal atherosclerosis, pulse wave velocity) will be measured in selected sites. Brain natriuretic peptide, adipose tissue cytokines, hsCRP and genetic markers are also under evaluation
Interventions
None listed
Sponsors
National Research Center for Preventive Medicine
Russian Cardiology Research and Production Center
Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
25 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
\- informed consent
Exclusion criteria
No
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| all cause mortality | 10 years | all cause motality registered by official statistics |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Stroke | 10 years | ischemic and heamorragic stroke |
| Miocardial infarction | 10 years | — |
| Cardiovascular mortality | 10 years | — |
Countries
Russia
Contacts
Primary ContactEugene V Shlyakhto, Prof
Backup ContactSergey A Boytsov, Prof
Outcome results
None listed