Blended Depression Therapy: Cognitive Behaviour Therapy Face-to-face and Via Internet

Conditions

Major Depressive Disorders

Keywords

Major Depressive Disorder (MDD), Blended treatment, Cognitive behavior Therapy (CBT), Face-to-face, internet-based treatment

Brief summary

To asses the clinical effectiveness of blended cognitive behavior therapy (CBT): face-to-face and internet-based treatment for adults with Major Depressive Disorder (MDD) in primary care compared to treatment as usual.

Detailed description

The study is part of a EU-project. Participants are recruited via regular routes from primary care settings. Following the Mini International Neuropsychiatric Interview (M.I.N.I.) participants will be randomly allocated to either blended treatment for 10 sessions/weeks or to treatment as usual. We will include 150 participants in total.

Asmae Doukani, Matteo Quartagno, Francesco Sera, Caroline Free, Ritsuko Kakuma et al. (26 authors)

Journal of Medical Internet Research2024-02-1118 citations

10.2196/47515

Examining the Theoretical Framework of Behavioral Activation for Major Depressive Disorder: Smartphone-Based Ecological Momentary Assessment Study

Claire van Genugten, Josien Schuurmans, Adriaan W. Hoogendoorn, Ricardo Araya, Gerhard Andersson et al. (23 authors)

JMIR Mental Health2021-12-069 citations

10.2196/32007

European COMPARative Effectiveness research on blended Depression treatment versus treatment-as-usual (E-COMPARED): study protocol for a randomized controlled, non-inferiority trial in eight European countries.

Kleiboer A, Smit J, Bosmans J, Ruwaard J, Andersson G, Topooco N, Berger T, Krieger T, Botella C, Baños R, Chevreul K, Araya R, Cerga-Pashoja A, Cieślak R, Rogala A, Vis C, Draisma S, van Schaik A, Kemmeren L, Ebert D, Berking M, Funk B, Cuijpers P, Riper H.

2016-08-0390 citations

10.1186/s13063-016-1511-1

Interventions

BEHAVIORALCognitive behavioral therapy

CBT based on behavioral activation and cognitive therapy techniques including homework

OTHERTreatment as usual

Treatment as usual in primary care including antidepressants and counselling

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

No

Inclusion criteria

* depressive symptoms according to DSM-IV * have access to a computer with internet connection * have good knowledge of the Swedish language

Exclusion criteria

* recent (during last 6 weeks) change in psychiatric medication * presently in any other psychological treatment * severe depression * suicidal ideation

Design outcomes

Primary

Measure	Time frame	Description
Quick Inventory of Depressive Symptomatology Self-Report (QIDS	Change from baseline in symptoms of depression. Time Frame: 0, 3, 6 and 12 months	Symptoms of depression measured by the QIDS. The QIDS is a questionnaire that screens for depressive symptoms and assesses depression severity.

Secondary

Measure	Time frame	Description
Client Satisfaction Questionnaire (CSQ-8)	Time Frame: 3 months (post treatment)	Patient's satisfaction with the treatment is assessed with Client Satisfaction Questionnaire (CSQ-8)
Credibility and Expectancy Questionnaire (CEQ)	Time Frame: 3 months (post treatment)	Patients' expectancy of treatment will be assessed with the credibility and expectancy questionnaire (CEQ)
System Usability Scale (SUS)	Time Frame: 3 months (post treatment)	Satisfaction with the internet platform will be evaluated with the system usability scale (SUS)
EuroQol-5D (EQ-5D-5L)	Time Frame: 0, 3, 6 and 12 months	Quality of life will be assessed with the EQ-5D-5L (EuroQol). The EQ-5D-5L is a self-report questionnaire which measures health related quality of life.
Working Alliance Inventory (WAI-SF)	Time Frame: 0 months ( three weeks after started treatment)	The therapeutic alliance between therapists and patient will be assessed with the short version of the Working Alliance Inventory (WAI-SF).
Trimbos and iMTA questionnaire on Costs associated with Psychiatric illness (TIC-P)	Time Frame: 0, 3, 6 and 12 months	Health service uptake and production loss due to illness will be measured with the Trimbos and iMTA Questionnaires on Costs Associated with Psychiatric Illness (TiC-P)
Patient Health Questionnaire (PHQ-9)	Time Frame: 0, 3, 6 and 12 months	The PHQ-9 is a nine-item mood module that can be used to screen and to diagnose patients with depressive disorders.

Countries

Sweden

Outcome results

None listed