Anemia, Malaria, Falciparum
Conditions
Brief summary
A cluster-randomized control trial will study the effect of insecticide-treated wall lining on malaria transmission in Bomi County, Liberia. Half of the villages enrolled in the study will receive insecticide-treated wall lining covering their walls and ceilings in addition to long-lasting insecticidal nets, while the other half will be protected by existing long-lasting insecticidal nets.
Detailed description
Long-lasting insecticidal nets (LLINs) are the established vector control product for malaria control. In Bomi County Liberia, LLINs have been distributed but malaria prevalence in children under 5 remains high, with prevalence in study villages found to be 42% in April 2014. The major malaria vector species are resistant to pyrethroid insecticides approved for use in LLINs, and new control measures with non-pyrethroid active ingredients may protect the population.
Interventions
DEVICEInsecticide treated wall lining
Polypropylene non-woven fabric.
Sponsors
Ministry of Health, Liberia
The Mentor Initiative
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Months to 59 Months
Healthy volunteers
Yes
Inclusion criteria
* Child resides in village * Child presents with parent or guardian
Exclusion criteria
* Child or guardian has history of Ebola exposure * Child has 3 symptoms of Ebola
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Malaria Prevalence | 6 months | Tested by mRDT and PCR |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hemoglobin | 6 months | Hemoglobin measured by Hemocue 301 |
| Fever | 6 months | Number of participants with Fever, defined as tympanic temperature above 37.5C |
| Mosquito biting rate. | 2 months | Mosquitoes trapped indoors and outdoors using light traps and exit traps. |
Countries
Liberia
Outcome results
None listed