Resistance Training in Patients With Parkinson's Disease.

Effects of Resistance Training on Bradykinesia and Physical Function in Patients With Parkinson's Disease.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02447146

Enrollment

Registered

2015-05-18

Start date

2013-01-31

Completion date

2014-12-31

Last updated

2015-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson Disease

Brief summary

This is a controlled trial to assess the effects of resistance training on bradykinesia and physical function in patients with Parkinson's Disease. Forty patients diagnosed with Parkinson Disease stage 1 to 3 of the Hoehn and Yahr scale took part in the study and were allocated into 2 groups; Training Group performed a 9-week RT program twice a week while the Control Group attended lectures on the disease.

Interventions

OTHERResistance Training

The TG performed the RT program using weight machines. Before the training period, participants underwent three weeks with eight familiarization sessions to ensure proper technique execution. The protocol aimed to workout major muscle groups and involved the following exercises: chest press, knee extension, hamstrings curl, leg press, and seated row. Training sessions lasted approximately 50-60 minutes with 2 sets of 10-12 repetitions until fatigue.

OTHERLectures on the disease

The control group attended an orientation program with lectures on health, quality of life and scientific update on disease.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

50 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Medical neurologist confirmation of 1-3 Hoehn and Yahr stages, * age between 50 and 80 years old; * and physician attested to participate in the resistance training program.

Exclusion criteria

* Diagnostic of any other neurological disease, cardiovascular disease, hematologic or orthopedic disorders; * and motor fluctuations or severe dyskinesia that could affect their ability to perform the experimental protocol.

Design outcomes

Primary

Measure	Time frame
Bradykinesia measured with Unified Parkinson's Disease Rating Scale, section III	One time point; after the end of 9-week resistance training
Functional Performance measured with Ten Meters Walk Test.	One time point; after the end of 9-week resistance training

Secondary

Measure	Time frame
Muscle strength measured with isokinetic peak torque.	One time point; after the end of 9-week resistance training

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026