Clinical Observation and MRI Influence of Acupuncture on Knee Osteoarthritis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02446756

Enrollment

Registered

2015-05-18

Start date

2010-01-31

Completion date

2014-02-28

Last updated

2015-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Arthritis Osteoarthritis

Keywords

Osteoarthritis, MRI, Cartilage, Acupuncture

Brief summary

To observe the therapeutic effect of acupuncture on osteoarthritis(OA) and its efficacy on cartilage restoration,acupuncture and physiotherapy treatment were respectively given to two random groups. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used to evaluate the motor function of knee joints, followed by magnetic resonance imaging (MRI) scanning to measure T2 values in ten cartilage sub-regions in tibiofemoral joints.

Detailed description

To observe the therapeutic effect of acupuncture on osteoarthritis and its efficacy on cartilage restoration,one hundred knees of 50 patients with knee osteoarthritis were randomly divided into acupuncture group and physiotherapy group which were respectively received acupuncture and physiotherapy treatment for four weeks. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used to evaluate the motor function of knee joints, followed by magnetic resonance imaging (MRI) scanning to measure T2 values in ten cartilage sub-regions in tibiofemoral joints.

Interventions

OTHERacupuncture

OTHERphysiotherapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

30 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Clinically diagnosed as knee osteoarthritis according to the OA criteria proposed by American College of Rheumatology in 1995.

Exclusion criteria

* Acute knee injury * Had ever accepted therapy as hormone or injection in articulation cavity * Had ever accepted treatment as oral medicine, physiotherapy, acupuncture or massage during the passed three months * Had planted cardiac pacemaker or any metal matter in body * Other severe diseases such as heart, lung, liver, kidney or cerebrum failure, tumors, gastrointestinal hemorrhage and so on * Pregnant or lactating woman * Anyone unable to tolerate or cooperate with treatment.

Design outcomes

Primary

Measure	Time frame
WOMAC scores	up to 24 months
T2 Values	up to 30 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026