Stroke
Conditions
Brief summary
The purpose now is to: 1. identify brain connections related to proprioception to have a better understanding of differences between people with stroke and healthy persons 2. evaluate how these brain connections will change in people with stroke when they are engaged in 6-week cognitive multisensory rehabilitation.
Interventions
Sponsors
University of Minnesota
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
Inclusion criteria for healthy subjects are: * medically stable; * 18 - 99 years of age; * able to hear the instructions given during the study Inclusion criteria for stroke patients are: * at least 6 months post-stroke; * medically stable; * 18 - 99 years of age; * subcortical or cortical infarct confirmed with MRI; * Mini-mental State Exam \> 24/30 (Folstein et al., 1975); * able to hear the instructions given during the study; * able to comprehend the instructions given during the study; * able to commit time to participate in a 6-12-weeks rehabilitation program
Exclusion criteria
* having ever experienced a stroke or another brain injury or illness related to the brain that has lasting effects or effects experienced at the moment of recruitment; * severe sensory impairments such that different movements of the finger, hand or wrist are not reliably felt; * contractures in tested arm that hinder persons from keeping the outstretched arm in a relaxed position; * interfering comorbidities (e.g. fracture, cancer, peripheral neuropathy); * exhibit contra-indications to enter the magnetic field of the 3T (pacemakers, metal parts in the body etc); * pregnant or nursing mother; * adults lacking capacity to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Preliminary study to measure the brain mechanisms of cognitive multisensory rehabilitation | 8 weeks | The robots will be used for research in healthy adults and stroke patients in the proposed studies below and are designed to mimick the exercises given during cognitive multisensory rehabilitation. The robots have been tested and cleared by the 3T safety committee at the CMRR, U of M. The first objective is a feasibility study to investigate the brain mechanisms of cognitive multisensory rehabilitation, through use of the robot in the 3T scanner at the U of M in healthy participants with stroke. Changes in brain function will be measured in individuals with stroke who will receive 8 weeks of therapy. |
Countries
United States
Outcome results
None listed