The Effect of Increased Water Intake on the Frequency of the Clinical Recurrent Urinary Tract Infections in Pre-menopausal Women: S-HYDRACYST

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02444975

Acronym

S-HYDRACYST

Enrollment

140

Registered

2015-05-15

Start date

2013-12-31

Completion date

2016-07-31

Last updated

2016-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Urinary Tract Infection

Keywords

Urinary Tract Infections, Water intake

Brief summary

The purpose of this study is to determine whether increased water intake is effective in preventing episodes of uncomplicated urinary tract infections (UTI) in pre-menopausal women suffering from UTI recurrences.

Detailed description

This study aims to assess the effect of increased daily water intake on the frequency of clinical, recurrent urinary tract infections (UTI) among low drinking pre-menopausal women suffering from recurrent community-acquired UTI over 12 consecutive months of study product consumption. It is a prospective, single site, open-label, randomised controlled trial in two parallel groups: * Control group: not changing their fluid intake habits * Intervention group: provided with mineral water, fluid intake recommendations and regular hydration coaching support The study population consists in pre-menopausal women diagnosed with recurrent UTIs and having a 'low drinker' profile. The total number of randomized subjects in this study is estimated at 140. The study will include only women who are low-drinkers (\< 1.5 L fluids per day; urinary volume \< 1.2 L per day) since they are most likely to have a predisposition to UTIs due to infrequent voiding.

Interventions

DIETARY_SUPPLEMENTMineral water

1.5L/day of water on top of the normal fluid intake for 1 year

OTHERCoaching program

Coaching program to support increased water intake

OTHERNo intervention

No intervention

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* At least 3 clinical recurrences of symptomatic UTI in the last 12 months * Age ≥ 18 years

Exclusion criteria

* Incapacity / non-willingness to consume 1.5 L of drinking water per day on top of their usual consumption * Women with history of UTI complications (pyelonephritis or other) in the last 12 months * Subjects with interstitial cystitis * Subjects with severe or uncontrolled organic disease, likely to interfere with the parameters of the study

Design outcomes

Primary

Measure	Time frame	Description
Incidence of UTI	12 months	Difference between groups in term of UTI recurrence over 12 months of study intervention

Countries

Bulgaria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026