The Feasibility of a Prehabilitation Program in the Liver Transplant Population at Barnes-Jewish Hospital

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02444273

Enrollment

101

Registered

2015-05-14

Start date

2014-10-31

Completion date

2017-12-31

Last updated

2018-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Liver Disease, Physical Activity

Keywords

liver diseases, liver transplantation, preoperative care, physical therapy

Brief summary

The primary outcome of this study is to demonstrate the feasibility of a prehabilitation program at Barnes Jewish Hospital for liver transplant candidates. Those patients who consent to participate in the study and are placed on the transplant list will be randomized into either the control or intervention group. The intervention group receives a personalized home exercise program along with weekly phone calls to provide coaching, mentoring and motivation. Data collected at baseline, post-transplant and, post-transplant follow up will be compared among the two study groups. The secondary outcomes include: normative data of functional measures for patients with end stage liver disease and to determine the effect size for future research on prehabilitation in the patient population.

Interventions

PROCEDUREExercise

Subjects will be given and individualized exercise program.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Yes

Inclusion criteria

* Being evaluated for liver transplantation by Barnes Jewish Hospital medical team

Exclusion criteria

* Non-english speaking * Medical contraindications to exercise as determined by the medical team

Design outcomes

Primary

Measure	Time frame	Description
Feasibility of a prehabilitation program.	2 Years	Feasibility will be measured by participation and outcome assessment measures.

Secondary

Measure	Time frame
Normative data on Timed Up and Go for patients with end stage liver disease.	Baseline
Normative data on 10 meter walk for patients with end stage liver disease.	Baseline
Normative data on Modified Dynamic Gait Index for patients with end stage liver disease.	Baseline
Normative data on Five Time Sit to Stand for patients with end stage liver disease.	Baseline
Normative data on 6 Minute Walk Test for patients with end stage liver disease.	Baseline

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026