Pain
Conditions
Brief summary
Nowadays Cesarean sections became the most popular surgery worldwide with the consumption of the hospital resources and the continuous need to decrease the costs, work load and medical stuff engagement. One of the most common problem is the need to control pain post operatively, this issue increase the work load over the pain management team and increase lead to patient in satisfaction. This study will test the usage of dexamethasone with different doses (4 and 8 mg) either locally or intravenously (I.V.) with the local anesthetics in TAP (transversus abdominis plane) block to prolong the duration of the block and decrease the need of post-operative analgesics.
Detailed description
Nowadays Cesarean sections became the most popular surgery worldwide with the consumption of the hospital resources and the continuous need to decrease the costs, work load and medical stuff engagement. One of the most common problem is the need to control pain post operatively, this issue increase the work load over the pain management team and increase lead to patient in satisfaction.(1,2,3) The presence of the adjuvant which can be added to the conventional anesthetic medications can prolong the duration of action and decrease the need for frequent post-operative analgesics.(4,5) The idea of adding a catheter or placing an epidural catheter still have a quite limitation regarding the patients compliance, delayed ambulation and high costs, these limitations redirect the anesthetist again to the use of adjuvant with a single shot block to prolong the duration of it and decrease the need of subsequent analgesics.(6) Dexamethasone proved to be an effective adjuvant in prolongation of the nerve blocks with the question regarding the proper route and dose (7,8,9,10). This study will test the usage of dexamethasone with different doses (4 and 8 mg) either locally or intravenously (I.V.) with the local anesthetics in TAP (transversus abdominis plane) block to prolong the duration of the block and decrease the need of post-operative analgesics.
Interventions
DRUGDexamethasone in addition to TAP block in dose of 4 mg
Dexamethasone in addition to TAP block in dose of 4 mg
DRUGDexamethasone in combination with TAP block in dose of 8 mg
Dexamethasone in combination with TAP block in dose of 8 mg
DRUGDexamethasone intravenous 4mg+ TAP block
Dexamethasone intravenous in addition to TAP block in dose of 4 mg
DRUGDexamethasone intravenous in addition to TAP block in dose of 8 mg
Dexamethasone intravenous + TAP block in dose of 8 mg
OTHERcontrol
TAP block without Dexamethasone neither intravenous nor in combination with the block
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Any patient ASA (american society of anesthesia) I or II, * aged between 18 and 45 scheduled for elective cesarean section.
Exclusion criteria
* patient refusal, * age below 18 or above 45 years, * coagulopathy with INR (international normalized ratio) more than 1.5 or platelets below 100000, * uncontrolled diabetes, uncontrolled hypertensive, addict patient, * psychological instability, and * allergy to the used drugs, * failure of spinal, * conversion to general of anesthesia, * failure of application of TAP block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| level of pain according to verbal analogue scale | THREE DAYS |
Countries
Egypt
Contacts
Primary ContactHassan Ali
Outcome results
None listed