Chronic Kidney Disease
Conditions
Keywords
Chronic Kidney Disease, Hemodialysis, Peritoneal Dialysis
Brief summary
Empowering Patients On Choices for Renal Replacement Therapy (EPOCH-RRT) study seeks to identify factors that matter the most to patients with kidney disease and study how they are impacted by different types of dialysis. The inclusion of patients, caregivers, and patient advocacy organizations as research partners will assure that the study addresses questions of greatest relevance to patients facing the need for dialysis. Aim two is based on preliminary results of Aim one interviews, and in collaboration with the Patient Advisory Panel, the investigators developed a brief questionnaire to be administered to participants in the Dialysis Outcomes and Practice Patterns Study (DOPPS) and Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS). Two separate versions of the questionnaire were created to reflect unique aspects of in-center hemodialysis (HD) and peritoneal dialysis (PD).
Interventions
None listed
Sponsors
University of Michigan
Henry Ford Health System
National Kidney Foundation, United States
American Association of Kidney Patients
Patient-Centered Outcomes Research Institute
Arbor Research Collaborative for Health
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Individuals 18 years of age or older. * Currently consented in the Dialysis Outcomes and Practice Patterns Study - (DOPPS) or the Peritoneal Outcomes and Practice Patterns Study (PDOPPS).
Exclusion criteria
* Individuals under 18 years of age. * Individuals unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient's Quality of Life | Baseline | % of patients very much or extremely affected by dialysis |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Hemodialysis (HD) Patients who have chronic kidney disease (CKD) and are currently on hemodialysis. | 1,346 |
| Peritoneal Dialysis (PD) Patients who have chronic kidney disease (CKD) and are currently on peritoneal dialysis. | 614 |
| Total | 1,960 |
Baseline characteristics
| Characteristic | Total | Peritoneal Dialysis (PD) | Hemodialysis (HD) |
|---|---|---|---|
| Age, Continuous | 62.06 years STANDARD_DEVIATION 14.66 | 59.90 years STANDARD_DEVIATION 14.92 | 63.04 years STANDARD_DEVIATION 14.44 |
| Age, Customized <=18 years | 0 participants | 0 participants | 0 participants |
| Age, Customized >=65 years | 878 participants | 229 participants | 649 participants |
| Age, Customized Between 18 and 65 years | 1070 participants | 384 participants | 686 participants |
| Region of Enrollment United States | 1960 participants | 614 participants | 1346 participants |
| Sex/Gender, Customized Female | 853 participants | 282 participants | 571 participants |
| Sex/Gender, Customized Male | 1097 participants | 331 participants | 766 participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | — / — | — / — |
| other Total, other adverse events | 0 / 0 | 0 / 0 |
| serious Total, serious adverse events | 0 / 0 | 0 / 0 |
Outcome results
Primary
Patient's Quality of Life
% of patients very much or extremely affected by dialysis
Time frame: Baseline
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Hemodialysis (HD) | Patient's Quality of Life | Relying on myself | 34 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Doing what I want in my free time | 35 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Spending time with people I care about | 34 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Doing activities that I am interested in | 28 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Traveling out of town | 45 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Maintaining a normal lifestyle | 27 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Managing my daily schedule | 21 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Keeping up with chores | 26 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Being energetic | 32 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Exercising | 22 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Maintaining my weight | 23 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Drinking as much water as I want | 46 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Eating what I like | 38 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Feeling healthy | 26 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Feeling attractive | 19 % of patients |
| Hemodialysis (HD) | Patient's Quality of Life | Getting enough sleep | 26 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Getting enough sleep | 22 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Relying on myself | 38 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Being energetic | 28 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Doing what I want in my free time | 27 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Eating what I like | 24 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Spending time with people I care about | 21 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Exercising | 20 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Doing activities that I am interested in | 21 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Feeling attractive | 17 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Traveling out of town | 42 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Maintaining my weight | 21 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Maintaining a normal lifestyle | 24 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Feeling healthy | 22 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Managing my daily schedule | 17 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Drinking as much water as I want | 24 % of patients |
| Peritoneal Dialysis (PD) | Patient's Quality of Life | Keeping up with chores | 24 % of patients |