Frontotemporal Dementia, Primary Progressive Aphasia
Conditions
Keywords
primary progressive aphasia, progressive nonfluent aphasia, progressive aphasia, frontotemporal dementia, frontotemporal lobar degeneration
Brief summary
This is a study on Internet-based video-practice speech and language therapy for persons with primary progressive aphasia (PPA), behavioral-variant frontotemporal dementia (bvFTD), or related conditions.
Detailed description
The purpose of this study is: 1. To evaluate the effectiveness of speech and language therapy on a person's ability to communicate immediately after treatment, 6-months after treatment, and 12-months after treatment. 2. To identify the most effective speech and language therapy strategies for persons with these conditions. 3. To determine the feasibility of Internet-based video-practice of speech and language therapy for persons with these conditions. The study will involve 12 to 15 session over the course of 12 months. Some of these sessions will be in-person at the Northwestern Cognitive Neurology and Alzheimer's Disease Center (Chicago, IL), while others will take place over the Internet, using an online study portal.
Interventions
BEHAVIORALMonthly Check-in Session
Subjects in the Check-In group will have an online session with a speech-language pathologist 3-, 4-, and 5-months from the subject's enrollment date.
Sponsors
Alzheimer's Association
The Association for Frontotemporal Degeneration
Illinois Department of Public Health
National Institutes of Health (NIH)
University of Chicago
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Diagnosis of dementia with language as a primary symptom (i.e. aphasia) * An informant who knows the participant well and can answer questions the participant's communication ability * Adequate hearing to follow conversation (correction permitted) * Adequate vision (correction permitted)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of Functional Communication Abilities | Change from baseline assessment at 2-months, 6-months and 12-months post-treatment | Functional Communication Abilities will be assessed through questionnaires about the participant's language and communication, neuropsychological testing, and speech and language therapy evaluations. |
Countries
United States
Outcome results
None listed