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Influence of Laminoplasty and Internal Fixation on Vertebral Stability After Laminectomy

Influence of Laminoplasty and Internal Fixation on Vertebral Stability After Cervical, Thoracic and Lumbar Laminectomy for Tumor Resection

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02436863
Enrollment
120
Registered
2015-05-07
Start date
2015-01-31
Completion date
2019-07-31
Last updated
2016-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorders Following Clinical Procedure

Keywords

Laminectomy, Laminoplasty, Internal fixation, deformity

Brief summary

The lesion located inside the spinal canal caused big trouble for clinical treatment. Traditional laminectomy will destroy the biomechanics and influent the vertebral stability, which might cause kyphosis or other deformity. So in some centers, neurosurgeries praised laminoplasty to make the intactness of posterior column. They thought the laminoplasty can maintain the vertebral stability, and meanwhile the range of motion won't change so much. However, some other scholars thought laminoplasty had no helps for stability because of the pseudarthrosis. They preferred screw and stick system for internal fixation. And we did meet several patients after laminectomy suffered with spinal deformity. So we thought it is necessary for investigating the benefit of patients from laminoplasty and internal fixation.

Detailed description

After laminectomy for removal of the cervical, thoracic and lumbar lesions, the recruited cases were randomly divided into two groups. 1. The cases in group of laminoplasty, the lamina and spinous process was replanted to maintain the anatomical intactness of spinal canal. 2. On the other hand, the cases in internal fixation group, the pedicle screws were implanted, and tickets were used to complete the internal fixation. During 3 years follow up, the vertebral deformity and the range of motion were investigated and evaluated. And in the meantime, the patient's age will also be analyzed to detect it's influence for the prognosis.

Interventions

PROCEDURESurgical performance

Two different surgical performances

Sponsors

Southern Medical University, China
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\- 1. Adult patients (\>=18 years) were enrolled. 2. The patients suffered with lesion inside the spinal canal, who underwent laminectomy to remove the lesion. 3\. Pathology proved benign lesion. 4. Health condition of patients (KPS) \>= 70.

Exclusion criteria

* 1\. Children cases (\<18 years) were excluded. * 2.The cases with pathological malignant tumors were excluded from this study. * 3\. KPS of patients \< 70.

Design outcomes

Primary

MeasureTime frame
Vertebral deformity3 years

Secondary

MeasureTime frame
The influence of age on the vertebral deformity3 years

Countries

China

Contacts

Primary ContactYuntao Lu, M.D., Ph.D
lllu2000@163.com+8613632101002
Backup ContactYiping Mo, Bachelor
+8620-61641806

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026