Esophagus Cancer, Gastric Cancer, Hypoxia, Oesophagitis, Peptic Ulcer
Conditions
Keywords
Sedation, Low pulse oximetry, Upper gastrointestinal endoscopy, WEI NASAL JET
Brief summary
Low pulse oximetry is the most common adverse events during sedation for upper gastrointestinal endoscopy. The main reason is the glossoptosis after sedation. In present study a new designed nasopharyngeal airway embedded with jet ventilation catheter(WEI NASAL JET) will be utilized in order to reduce the hypoxia. At the same time the safety will be evaluated.
Interventions
DEVICEWEI NASAL JET
Oxygen is supplied through WEI NASAL JET by a manual jet ventilator
DEVICENasopharyngeal airway without jet ventilator
Oxygen is supplied directly through WEI NASAL JET without jet ventilator
Sponsors
Shanghai Pudong New Area People's Hospital
Shanghai Tongji Hospital, Tongji University School of Medicine
RenJi Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients undergoing upper gastrointestinal endoscopy * age over 18 years old * Signed informed consent form
Exclusion criteria
* a blood coagulation dysfunction or have a tendency of nose bleeding * a clear diagnosis of heart disease (heart failure, angina, myocardial infarction, arrhythmia, etc.) * a clear diagnosis of lung disease (asthma, chronic obstructive pulmonary disease, pulmonary embolism, pulmonary edema, lung cancer) * pregnant * liver disease * kidney disease * increase in intracranial pressure * emergency operation * multiple trauma * American Society of Anesthesiologists (ASA) Physical Status classification above IV * with mouth, nose and throat infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Low pulse oximetry incidence | Patients will be followed for the duration of hospital stay, an expected average of 2 hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Other adverse events | Patients will be followed for the duration of hospital stay, an expected average of 2 hours | The adverse events according to the Adverse event reporting tool of the world SIVA International Sedation Task Force during upper gastrointestinal endoscopy will be recorded. Adverse events associated with jet ventilation also be recorded. |
Countries
China
Contacts
Primary ContactDiansan Su, Dr.
Outcome results
None listed