Heart Failure
Conditions
Brief summary
The purpose of this study is to determine if detailed scanning of the heart before biventricular device insertion will improve outcomes for heart failure patients.
Interventions
OTHERHeart scan
Sponsors
University College, London
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
1. Age \> 18, \<90 2. Patients with moderate or severe heart failure ( NYHA functional class II-IV) due to ischaemic or non-ischaemic cardiomyopathy. 3. QRS duration \>120ms on 12 lead ECG 4. LVEF \< 35% 5. LVEDD \>55 mm 6. Patients on optimum medical treatment for heart failure. The doses of these medications have been stable for 3 months.
Exclusion criteria
1. Patients with a cardiac or cerebral ischemic event within the previous three months prior to recruitment 2. Patients who had had an atrial arrhythmia within one month prior to recruitment 3. Patients with a systolic blood pressure of more than 170 or less than 80 mm Hg 4. Patients with a heart rate of more than 140 beats per minute 5. Patients with severe renal failure (eGFR \< 30) 6. Patients with a history of allergy to iodine based contrast agents 7. Predicted life expectancy \< 1 year 8. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6 minute walk test | 6 months |
Countries
United Kingdom
Contacts
Primary ContactVanessa Cobb
Outcome results
None listed