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Risk Factors for Acquired Cardiovascular Disease in Adults With Congenital Heart Disease

Risk Factors for Acquired Cardiovascular Disease in Adults With Congenital Heart Disease

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02433990
Enrollment
178
Registered
2015-05-05
Start date
2014-04-30
Completion date
2019-08-24
Last updated
2019-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Heart Disease

Keywords

Congenital Heart Disease, Acquired Cardiovascular Disease

Brief summary

This research study is to determine the risk factors for acquired heart disease, in adults with congenital heart disease. This knowledge is important to develop and target ways to prevent or delay the onset of acquired heart disease in adults with congenital heart disease.

Detailed description

Advances in surgical and clinical management of patients with congenital heart disease has made survival to adulthood an expectation. Today there are more than 1 million adult survivors of congenital heart disease, but increasing age brings additional concerns for this patient population. Although the literature remains scarce, existing evidence suggests that inactivity, obesity, diabetes, cancer, and acquired cardiovascular disease may be at least as prevalent in patients with congenital heart disease, if not more so, than in an age-matched general population. Acquired cardiovascular disease is likely to impact substantially on long-term survival and quality of life in these patients with palliated and already fragile hearts. This research study is to determine the risk factors for acquired heart disease, in adults with congenital heart disease. This knowledge is important to develop and target ways to prevent or delay the onset of acquired heart disease in adults with congenital heart disease.

Interventions

None listed

Sponsors

Stanford University
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Male or Female over 18 years of age * Moderate or Complex Congenital Heart Disease * Willingness to Consent

Exclusion criteria

* Pregnancy * Surgery within 6 months * Unrepaired cyanotic heart disease * Patients with Eisenmenger Syndrome physiology

Design outcomes

Primary

MeasureTime frame
Risk factors for acquired cardiovascular disease in adults with congenital heart disease2 years

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026