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Pre-meal Planning and Expected Satiety

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02427152
Enrollment
60
Registered
2015-04-27
Start date
2015-03-31
Completion date
2017-12-31
Last updated
2017-05-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adiposity

Brief summary

Obesity is considered to be caused by an imbalance between energy expenditure and energy intake. A major determinant of our daily energy intake is the size of the meals that we consume. It has been suggested that decisions about portion sizes are often made in advance, before a meal begins. This pre-meal planning is considered to especially depend on the estimated 'expected satiety' and 'expected satiation' of different foods. Further, also factors like weight concern and palatability of the food might have their influence on meal size selection. In general, it is not clear how these factors are integrated during pre-meal planning and which brain networks are involved in these decisions/this process. Thus, the investigators plan to study pre-meal planning in healthy, normal-weight and overweight/obese individuals with functional magnetic resonance imaging under different cognitive instructions including pleasure, expected satiety and self-control in terms of health consequences. The investigators will explore the neural networks involved in pre-meal planning and expect them to be modulated by the before mentioned factors. Further, the investigators plan to explore gender differences and expect that female subjects will select smaller portion sizes especially in the self-control condition as they are often more concerned about their weight/health. Finally, the investigators will explore differences between lean and overweight subjects to elucidate factors that might lead to increased meal sizes in overweight subjects.

Interventions

None listed

Sponsors

University Hospital Tuebingen
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* body mass index: 18-25 kg/m²; 25-35 kg/m², * right-handed, * age: 18-35 years.

Exclusion criteria

* functional magnetic resonance imaging contraindications, * claustrophobia, * self-reported eating disorders, * vegan or vegetarian diet, food allergies, * intake of antidepressants, * metabolic disorders.

Design outcomes

Primary

MeasureTime frameDescription
Differential brain functions in reward, decision making and inhibitory control networks (brain functions will be measured by blood oxygen level dependent effects)day 0brain functions will be measured by blood oxygen level dependent effects

Secondary

MeasureTime frame
Differential behavioral measures of portion size selectionday 0

Countries

Germany

Contacts

Primary ContactHege
maike.hege@med.uni-tuebingen.de

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026