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Artificial Oocyte Activation Comparing Tow Different Agents

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02424214
Enrollment
450
Registered
2015-04-22
Start date
2015-04-30
Completion date
2016-01-31
Last updated
2018-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oocyte Fertilization

Brief summary

Comparing the efficacy of tow factors for artificial Oocyte Activation for poor quality Oocytes and Teratozoospermia patients.

Detailed description

The IVF outcome had been varied widely with a good portion of total fertilization failure even after the most advanced procedure for this group of patient Intracytoplasmic Sperm Injection, many factors that had been tested for assisting the failed group of patient to be fertilized artificially like Ca Ionophore, Strontium Chloride and others but we decide to compare the clinically proven factors for the efficacy and safety in a well randomized clinical trial and monitor the embryogenesis and pregnancy within the 2 groups.

Interventions

DRUGCa Ionophore
DRUGStrontium Chloride

Sponsors

Al Baraka Fertility Hospital
CollaboratorOTHER
Banon IVF Center Assiut, Egypt
CollaboratorOTHER
Ibn Sina Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* previous fertilization failure * poor quality Oocytes * poor sperms

Exclusion criteria

* normal patients

Design outcomes

Primary

MeasureTime frame
Pregnancy rate ( % )9 months

Secondary

MeasureTime frame
Blastocyst rate ( % )9 months

Countries

Bahrain, Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 5, 2026