Infertility
Conditions
Keywords
IVF, endometrial thickness, cleavage stage embryo, blastocyst stage embryo, Ongoing pregnancy rate
Brief summary
Although many studies have evaluated the relationship between endometrial thickness and IVF outcome, the results are still controversial. We notice that, during our daily work, for patients undergoing cleavage stage embryo transfer, endometrial thickness seems to have a huge impact on IVF outcome; however, for blastocyst stage embryo transfers, IVF outcome seems to have little association with endometrial thickness. Thus, the aim of this prospective observational study is to explore the relationship between endometrial thickness and IVF outcome in patients undergoing cleavage stage and blastocyst stage embryo transfers, respectively.
Interventions
PROCEDUREEmbryo transfer
For fresh cycles, embryos were transferred 3-5 days after oocyte retrieval; For frozen thawed cycles, embryos were transferred 3-5 days after starting to use progesterone based on the stage of cryopreservation.
Sponsors
The First Affiliated Hospital of Zhengzhou University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
22 Years to 38 Years
Healthy volunteers
No
Inclusion criteria
* age between 22-38 years old; * the first cycle of IVF treatment with standard long protocol; * transfrred with at least two high quality cleavage stage embryos, or with at least one high quality blastocyst stage embryo.
Exclusion criteria
* PGD cycles; * gamete donation cycles
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ongoing pregnancy rate | 12 weeks after embryo transfer | An ongoing pregnancy was defined as a pregnancy with a positive heartbeat by ultrasound after 12 weeks gestation. |
Countries
China
Contacts
Primary ContactZhiqin Bu, M.D
Backup ContactYingpu Sun, M.D
Outcome results
None listed