Failed Induction of Labor
Conditions
Keywords
membrane sweeping, dinoprostone, nulliparas, labor induction
Brief summary
To compare concurrent oxytocin with membrane sweeping versus dinoprostone pessary in labor induction for nulliparas at term with an unfavorable cervix
Interventions
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* singleton pregnancy * Nulliparous women * gestational age \>=37.0 weeks * Bishop score \<=6 * intact amniotic membrane * absence of labor * live fetus with vertex presentation * no previous uterine surgical procedure
Exclusion criteria
* Multiple pregnancy * Placenta previa
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vaginal delivery within 24 hours | From the time of initiating intervention (i.e.concurrent membrane sweeping with dinoprostone or only dinoprostone) until the time of vaginal delivery, assessed up to 24 hours | Vaginal delivery within 24 hours is defined as vaginal delivery after 24 hours of initiating intervention (i.e.concurrent membrane sweeping with dinoprostone or only dinoprostone) on the first day of induction. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Successful labor induction | From the time of initiating intervention (i.e.concurrent membrane sweeping with dinoprostone or only dinoprostone) until the time of active phase of labor ( defined as a cervical dilatation of >=4cm), assessed up to 24 hours | to achieve the active phase of labor corresponding to a cervical dilatation of \>=4cm |
| Incidence of cesarean delivery | End of labor induction (assessed up to 120 hours) | From the time of initiating intervention (i.e.concurrent membrane sweeping with dinoprostone or only dinoprostone) until the time of cesarean delivery, assessed up to 120 hours |
| The interval from start of oxytocin to delivery | From the time of initiating oxytocin infusion until the time of delivery, assessed up to 120 hours | — |
Countries
South Korea
Outcome results
None listed