Immunity Improvement Effect of Ulmus Macrocarpa Water Extract in Adults

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02414412

Enrollment

Registered

2015-04-10

Start date

2015-02-28

Completion date

2015-05-31

Last updated

2015-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Ulmus macrocarpa water extract, immunity

Brief summary

This randomized, placebo-controlled, double-blind study evaluates the efficacy and tolerability of Ulmus macrocarpa water extract for immunity improvement in relatively healthy adults. 58 subjects received 500 mg of Ulmus macrocarpa water extract per day or a placebo for 4 weeks.

Interventions

DIETARY_SUPPLEMENTUlmus macrocarpa water extract

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

19 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* subject has peripheral white blood cells between 4,000/Ul and 8,000/Ul

Exclusion criteria

* History of renal disease * History of diabetes mellitus * History of immune disease

Design outcomes

Primary

Measure	Time frame
serum natural killer cell activity	1 month

Secondary

Measure	Time frame
peripheral white blood cell	1 month
serum tumor necrosis factor-alpha level	1 month
serum interferon-gamma	1 month
serum interleukins(1betta, 2,4,8,10, and 12)	1 month

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026