Medication Reconciliation in Comparison to an Extensive Medication Safety Check

Pilot Project to Investigate the Influence of Medication Reconciliation and an Extensive Medication Safety Check on the Number of Adverse Drug Events in the Elderly

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02413957

Enrollment

220

Registered

2015-04-10

Start date

2015-01-31

Completion date

2016-01-31

Last updated

2017-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adverse Drug Event, Elderly

Keywords

Elderly Patients, Medication Safety, Pharmaceutical Care, Medication Reconciliation

Brief summary

The purpose of this study is to determine wether an extensive medication safety check has a greater impact on the incidence of adverse drug events than medication reconciliation or no intervention.

Interventions

OTHERMedication Reconciliation

Pharmacist take the best possible medication history (BPMH), comparison of the BPMH with the admission order (AMO), clarify and solve al discrepancies between the BPMH and the AMO.

OTHERPharmaceutical Care

Checking medication under safety considerations (medication at admission, during hospital stay, at discharge); recommendations for inappropriate medication (e.g. contraindications or interactions) or medication related problems. Pharmaceutical care includes Medication Reconciliation.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient 65 years and older * written informed consent patient or the legal representative * existing medication therapy at hospitalization * admission to one of the project wards via emergency department (non elective)

Exclusion criteria

\- patients included in the study previously

Design outcomes

Primary

Measure	Time frame
incidence of adverse drug events	1 year

Secondary

Measure	Time frame	Description
Assessment of the clinical relevance of medication related problems as determined by the French Society of Clinical Pharmacy	1 year	Severity scale for medication related problems: minor, significative, major, critical, catastrophic
Assessment of the clinical relevance of discrepancies as determined by the French Society of Clinical Pharmacy	1 year	Severity scale for discrepancies: minor, significative, major, critical, catastrophic
number of medication related problems	1 year	—
number of discrepancies	1 year	—
duration of taking the best possible medication history	1 year	The duration is measured in minutes.

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026