Intratracheal Intubation in Critical Care
Conditions
Keywords
intubation, critical care, laryngoscope, videolaryngoscope, intratracheal
Brief summary
The aim of this study is to demonstrate that the rate of successful orotracheal intubation at first laryngoscopy will be higher in patients intubated with McGrath Mac videolaryngoscope compared to patients intubated with classical Macintosh laryngoscope in patients requiring an orotracheal intubation in ICU.
Interventions
DEVICEVideolaryngoscope
McGrath Mac videolaryngoscope will be use for first attempt of intratracheal intubation.
DEVICEStandard laryngoscope
Macintosh laryngoscope will be use for first attempt of intratracheal intubation.
Sponsors
Nantes University Hospital
Centre Hospitalier Departemental Vendee
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• Requiring orotracheal intubation
Exclusion criteria
* Contraindication to orotracheal intubation * Time too short to allow inclusion and randomisation of patient (particularly cardiac arrest) * Minor (\<18 ) * Pregnant, parturient , or breast-feeding woman * Patient hospitalized without consent and/or deprived of liberty by court's decision * Patient under guardianship or curators * Lack of social insurance * Lack of informed consent * Concomitant inclusion in a trial whose primary endpoint focuses on intubation procedure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of successful orotracheal intubation at first laryngoscopy | intubation procedure, an expected average of 15 minutes | Number of successful intubation at first laryngoscopy in one arm/number of included patients in the same arm. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of successful orotracheal intubation all laryngoscopies pooled | intubation procedure, an expected average of 15 minutes | — |
| Time to successful orotracheal intubation | intubation procedure, an expected average of 15 minutes | Defined by the time between the beginning of induction (injection of anesthetic drugs) and the time of confirmation of the intratracheal nature of the endotracheal tube (defined as apparition of first inflexion on the expired carbon dioxide curve) |
Other
| Measure | Time frame |
|---|---|
| Resort to alternative intubation technique | intubation procedure, an expected average of 15 minutes |
| Frequency of occurence of unexpected events | Discharge from Intensive Care unit, an expected average of 7 days |
| Mechanical ventilation duration | Time from extubation, an expected average of 6 days |
| Cormack and Lehane grade | intubation procedure, an expected average of 15 minutes |
| Hospital length of stay | Discharge from hospital, an expected average of 14 days |
| Intensive Care Unit Mortality | Discharge from Intensive Care unit, an expected average of 7 days |
| Mortality at day 28 | Day 28 |
| Intensive Care Unit length of stay | Discharge from Intensive Care unit, an expected average of 7 days |
| Percentage of glottic opening (POGO) score | intubation procedure, an expected average of 15 minutes |
| Difficult Intubation | intubation procedure, an expected average of 15 minutes |
Countries
France
Outcome results
None listed