Sublingual Microcirculation of Healthy Volunteers by Using the Third Generation Microcirculation Video Microscope

Population Research of Sublingual Microcirculation Data of Healthy Volunteers by Using the Third Generation Microcirculation Video Microscope

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02412839

Enrollment

150

Registered

2015-04-09

Start date

2015-04-30

Completion date

2017-02-28

Last updated

2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

This study will enroll 150 healthy volunteers, and the grouping is as follows: group 20-39 (30 males and 30 females); group 40-59 (30 males and 30 females); and group 60-79 (15 males and 15 females). The sublingual microcirculation will be examined with the incident dark field video microscope (Cytocam，Braedius Battery Powered Transilluminator). The study aims to compare the differences of microcirculation among the three groups and between genders.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

20 Years to 79 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy volunteers aged from 20 to 79 years old * BMI ranged from 18.5 to 27 kg/m2

Exclusion criteria

* Systolic blood pressure \> 140 mm Hg, diastolic blood pressure \> 95 mm Hg, or systolic blood pressure \< 90 mm Hg at enrollment * Body temperature \> 37.5 ℃ or \< 35.5 ℃ at enrollment * had been diagnose with any one of the following diseases * hypertension * diabetes mellitus * peripheral arterial occlusive disease * coronary arterial disease * liver cirrhosis * chronic kidney disease * stroke * anemia * asthma * chronic bronchitis * any metabolic diseases * any hematologic disease * uncured cancer * chronic uncontrolled infection * other disease may limit daily activities * non-native speakers

Design outcomes

Primary

Measure	Time frame	Description
Total small vessel density of sublingual small vessels measured by Cytocam	Once at enrollment	Total small vessel density will be measured by Cytocam

Secondary

Measure	Time frame	Description
Perfused small vessel density of sublingual small vessels measured by Cytocam	Once at enrollment	Perfused small vessel density will be measured by Cytocam

Countries

Taiwan

Outcome results