Overweight and Obesity
Conditions
Brief summary
To study the effects of Flaxseed supplement on weight, lipid profile and inflammatory factors in subjects with over weight and obesity, 50 patients will be randomly allocated to receive placebo or 30 grams milled Flaxseed for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, weight, waist and hip circumference, lipid profile and some inflammatory markers will be assessed and compared between groups.
Interventions
DIETARY_SUPPLEMENTflaxseed
DIETARY_SUPPLEMENTPlacebo
BEHAVIORALExercise recommendation
Sponsors
National Nutrition and Food Technology Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Age of 18 to 70 years * Body Mass Index (BMI) between 25-40
Exclusion criteria
* diabetes mellitus * cardiovascular diseases and cancers * major systemic diseases * gastrointestinal problems * liver and renal failure * history of allergy or high consumption of nuts, flaxseed, or sesame seeds * weight loss within the past 6 mo of \>5% of body weight or current adherence to a weight-reduction diet * pregnancy, lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weight | 12 weeks |
| waist and hip circumference | 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| lipid profile | 12 weeks |
Outcome results
None listed