Chronic Disease, Refractory, Sinusitis
Conditions
Brief summary
To analyse and describe sinus microbiota, during hard to treat (or refractory) rhinosinusitis, using culturomic and metagenomic methods (i.e. to culture on many different medium of culture to grow hard to cultivate bacteria + to sequence and analyse all DNA contained in samples). Samples are middle meatus swabs or pus aspiration, done during usually patient following.
Interventions
OTHERBiological sample
Sponsors
University Hospital, Marseille
Institut Hospitalo-Universitaire Méditerranée Infection
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \>18 year old * chronic refractory rhinosinusitis * to require middle meatus swab or other sinus sample * absence of opposition
Exclusion criteria
* \<18 year old * pregnant women * breastfeeding * under trusteeship * under guardianship
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sinusian microbiota description | 6 months | species, number and type of isolated microbes |
Countries
France
Contacts
Primary ContactErwan Le Dault
Backup ContactPierre-Edouard Fournier, Professor
Outcome results
None listed