Oropharyngeal Cancer
Conditions
Brief summary
The objective of this research is to perform a pilot study on patients undergoing laryngoscopy for diagnostic and tumor staging purposes (for pharyngeal or laryngeal cancer) in which intraoperative CT imaging will be performed both prior to (but after induction of general endotracheal anesthesia) and during placement of the laryngoscope in order to better understand anatomic changes that occur during instrumentation of the oral cavity and oropharynx. The goals of the study are: 1. Develop a suite of de-identified images and surface renderings that qualitatively show how a tumor and the upper aerodigestive tract anatomy deform during a laryngoscopic evaluation. 2. Create deformation models of the upper aerodigestive tract. This data to be used for future retractor development as well as for virtual image guided surgery.
Interventions
OTHERIntraoperative CT imaging
Intraoperative CT scan of the upper aerodigestive tract during laryngoscopy procedure
Sponsors
Dartmouth-Hitchcock Medical Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients (\>18 years) seen in the Head and Neck Tumor Clinic who will require laryngoscopy in the operating room for diagnosis and staging of known or suspected tumors of the upper aerodigestive tract.
Exclusion criteria
* Patients who are unable to tolerate general anesthesia. * Patients who are felt to be a difficult airway for induction of general endotracheal anesthesia. * Patients with excessive dental restorations and amalgam.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Radiographic evidence of upper aerodigestive tract deformation during laryngoscopy | Collected at the time of surgery |
Countries
United States
Outcome results
None listed