Hodgkin's Lymphoma
Conditions
Keywords
Radiation, Cardiac, Hodgkin's lymphoma
Brief summary
The purpose of this study is to evaluate if radiation and chemotherapy treatment cause cardiac abnormalities among survivors of Hodgkin's lymphoma.
Interventions
PROCEDURECardiac Magnetic Resonance Imaging
A cardiac MRI will be performed.
PROCEDUREEchocardiogram
An echocardiogram will be performed for the following information: M-mode, two-dimensional, Doppler blood flow measurements, and longitudinal strain and strain rate imaging
Sponsors
University of Florida
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Completed radiation and chemotherapy treatment for Hodgkin lymphoma involving the mediastinum. * Patient must be ≥ 18 years at time of consent.
Exclusion criteria
* Pregnant women at time of Cardiac MRI * Contraindications to Cardiac MRI (contrast allergy, metal implants, medical devices) * Glomerular filtration rate (GFR) \< 30, unless approved by Radiologist (UF Health Jacksonville Radiology Policy: Administration of Gadolinium-Based Contrast Agents).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac Abnormalities As Measured By Cardiac MRI | Day 1 |
| Cardiac Abnormalities As Measured By Echocardiogram | Day 1 |
Countries
United States
Outcome results
None listed