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Effects of C0-C1 Mobilization in the Neutral Position in Subjects With Upper Cervical Rotational Hypomobility

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02404766
Enrollment
48
Registered
2015-03-31
Start date
2012-12-31
Completion date
2015-03-31
Last updated
2015-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper Cervical Spine Rotational Hypomobility

Keywords

manual therapy, cervical, range of movement

Brief summary

C1-C2 is the most mobile segment of the spine and its dysfunction is frequently associated to cervical pain and headache. However, serious neurovascular adverse effects have been documented through direct treatment of C1-C2 segment. Although indirect treatment via adjacent segments and avoidance of end range of rotation and extension have been recommended for a safer and effective cervical treatment, there is no scientific evidence of the effectiveness of the indirect treatment approach in the cervical neutral position for C1-C2 hypomobility. Due to that, the investigators designed a randomized controlled trial to compare the short-term effects in the Flexion Rotation Test (FRT) of a translatoric mobilization of C0-C1, a translatoric mobilization of C7-T1 and a control group in subjects with C1-C2 hypomobility.The primary hypothesis is that C0-C1 dorsal glide mobilization applied in the neutral cervical position can recover the C1-C2 rotational range of movement in subjects with upper cervical hypomobility.

Interventions

OTHERC0-C1 dorsal glide manual mobilization
OTHERC7-T1 ventral cranial glide manual mobilization

Sponsors

Universidad de Zaragoza
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 66 Years
Healthy volunteers
Yes

Inclusion criteria

* FRT with less than 32º or asymmetry of 10º between right and left, whenever one of the sides does not exceed physiological C1-C2 ROM (45º) * Indication of grade III mobilization in C0-C1 and C7-T1 segments * Aged 18-66 * Signed informed consent

Exclusion criteria

* Contraindication to manual therapy and red flags according to Rushton et al. (2012) * Pain presence at the beginning or during the study * Cervical treatment during the last three months * Inability to tolerate FRT * Involvement in litigation or compensation

Design outcomes

Primary

MeasureTime frameDescription
Change in baseline in Range of movement in Upper Cervical Spine1 hour after interventionFlexion-rotation test measured by CROM device

Secondary

MeasureTime frameDescription
Cervical range of movement in cardinal planes1 hour after interventionActive cervical range of movement in sagittal, frontal and transversal planes measured by CROM device.
Upper cervical flexion and extension range of movement1 hour after interventionActive upper cervical flexion and extension range of movement measured with CROM device

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026