Hydrocephalus
Conditions
Keywords
VP shunted, Normal intracranial pathology, patients
Brief summary
Using a pulse oximeter, we have developed an algorithm that estimates intracranial pressure (ICP) based on patients who have had traumatic brain injuries. Patients with hydrocephalus are typically treated with a shunt in order to reduce ICP. At times the shunt can malfunction. We believe that our algorithm will help identify when a hydrocephalus patient's shunt has malfunctioned.
Detailed description
A malfunctioning ventriculoperitoneal (VP) shunt will typically cause a rise in intracranial pressure, which can be difficult to identify without costly imaging. Novel, state-of-the art machine learning techniques can be leveraged to develop an algorithm that noninvasively estimates intracranial pressure. The resulting algorithm will accurately determine the presence or absence of ventriculoperitoneal shunt malfunction in patients with hydrocephalus.
Interventions
DEVICEPulse oximetry
Pulse oximetry
Sponsors
University of Colorado, Denver
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
31 Days to 35 Years
Healthy volunteers
No
Inclusion criteria
1. Age: 31 days - 35 years 2. Patients seen at Children's Hospital Colorado Neurosurgery clinic, Emergency Department or on an inpatient service 3. Either hydrocephalus patients with a VP shunt in place (with or without suspicion of VP shunt malfunction), or patients with no known intracranial pathology.
Exclusion criteria
1. Pregnant patients 2. Incarcerated patients 3. Patients who object at any time to participating in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The presence or absence of ventriculoperitoneal shunt malfunction in patients with hydrocephalus | baseline | The algorithm development |
Outcome results
None listed