Patients With Postoperative Mechanical Ventilation After Liver Transplantation
Conditions
Brief summary
Mechanical ventilatory lung care is essential for postoperative care in liver transplantation recipients, for such patients are under massive fluid challenge and hemodynamic alterations perioperatively. Some of the recipients experience difficulty in weaning off from the mechanical ventilator due to various causes. This study is to investigate the relationship between the inflammatory gene polymorphism, known for acute lung injury, and the duration of mechanical ventilatory care for such liver transplantation recipients.
Interventions
OTHERMechanical ventilatory lung care
Sponsors
Yonsei University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1. 20-65 years old 2. scheduled for liver transplantation
Exclusion criteria
1. Patients under mechanical ventilation prior to surgery 2. patients with muscular skeletal disorder, probable cause for respiratory depression 3. patients not able to read, or understand the consent form 4. ethnicity, other than asian 5. patients refusal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| total duration of postoperative ventilator care | an expected average of 2-3 days | Time for successful weaning from ventilator could correlate with the inflammtory gene polymorphism, especially those related to acute lung injury. |
Countries
South Korea
Outcome results
None listed