Prostate Cancer
Conditions
Brief summary
Comparing postoperative analgesics requirements and complications between conventional and model-based infusion strategy of intravenous patient-controlled analgesia in patients who undergoing robot assisted laparoscopic radical prostatectomy Group A: conventional intravenous patient-controlled analgesia, Group B: model-based infusion strategy of intravenous patient-controlled analgesia
Detailed description
The investigators compared postoperative analgesics requirements and complications between conventional and model-based infusion strategy of intravenous patient-controlled analgesia (IV PCA) in patients who undergoing robot assisted laparoscopic radical prostatectomy (RALP) Group A: conventional IV PCA, Group B: model based IV PCA 1. Primary endpoint: comparison of postoperative analgesic requirements in patient undergoing robot assisted laparoscopic radical prostatectomy (RALP) between conventional patient controlled analgesia (PCA) (Group A) and effective-compartment based dosing strategy of PCA (Group B) 2. Secondary endpoint: 1) VAS analysis between two groups, 2) postoperative nausea and vomiting analysis between two groups, 3) complication evaluation between two groups
Interventions
DRUGfentanyl
fentanyl with antiemetic drug
Sponsors
Asan Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
20 Years to 69 Years
Healthy volunteers
No
Inclusion criteria
* Patient who is scheduled to get a robot assisted laparoscopic radical prostatectomy * Patient who agree to get a patient controlled analgesia
Exclusion criteria
* American Society of Anesthesiologist (ASA) physical status over III * History of alcohol or drug addiction * History of acute or chronic pain or pain treatment * Allergic to opioid analgesics * BMI over 30 kg/m2 * History of sleep apnea or respiratory complications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount and number of postoperative analgesic requirements | Participants will be followed for the duration of hospital stay, an expected average of 1 week |
Secondary
| Measure | Time frame |
|---|---|
| Number of participants with complications | Up to 48 hours |
| Visual Analog Scale (VAS) | Up to 48 hours |
| Postoperative nausea and vomiting | Up to 48 hours |
| Respiratory rate, oxygen saturation | Up to 48 hours |
Countries
South Korea
Outcome results
None listed