Diabetes, Obesity
Conditions
Keywords
Diabetes Prevention, Obesity Prevention
Brief summary
The objectives are to test the acute effects of different extruded pulse snacks on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite on an aerobic exercise session, and 3) food intake two hours following the exercise session. The investigators hypothesize that consumption of food products containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. The investigators also hypothesize that consumption of extruded pulse snacks will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.
Interventions
OTHERControl
Non pulse extruded snack
Pulse extruded snack
Pulse extruded snack
OTHERLentil flour
Pulse extruded snack
OTHERNavy bean flour
Pulse extruded snack
OTHERPinto bean flour
Pulse extruded snack
Sponsors
Saskatchewan Pulse Growers
Alberta Pulse Growers
University of Manitoba
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Normoglycemic (\<5.6 mmol/L) and normotensive (systolic blood pressure \<140 mm Hg and diastolic blood pressure below \< 90 mm Hg) * BMI of 18.5-29.9 kg/m2
Exclusion criteria
* Restrained eaters * Regularly skip breakfast * Smokers * Those who are active (organized activities or athletic training at a high intensity; ≥ 150 min per week of moderate to vigorous physical activity) * Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year. * Those unable to walk for an hour continuously
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma Glucose and Insulin Concentrations | 0 - 240 min | Measured in blood using intravenous catheter at 14 time points, used to calculate area under curve (AUC). Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits. (Composite measure) |
| Food Intake | at 120 min | Ad-libitum meal. Food consumed measured by weight. |
| Subjective Appetite | 0-240 min | Measured by VAS questionnaire at 14 time points, used to calculate area under curve (AUC).( Composite measure) |
| Exercise intensity | 60 minutes | Sixty minute exercise protocol at minutes 60 to 120. Oxygen consumption measured during exercise at 3 time points. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Energy/fatigue | 0-240 min | Measured by VAS questionnaire at 13 time points, used to calculate area under curve (AUC) (Composite measure) |
| Lactate concentration | 60 minutes | 60 minute exercise protocol at minutes 60 to 120. Measured before, during, and exercise exercise at 3 time points |
| Substrate Oxidation | 60 minutes | Measured during 60 minute exercise protocol at minutes 60-120. Respiratory quotient measured during exercise at 3 time points. |
| Heart rate | 60-120 min | Heart rate monitored over a 60 minute exercise protocol. To monitor exercise intensity and give a measure of fatigue (cardiovascular drift) |
| Palatability of treatments | at 5 minutes | Measured by VAS questionnaire |
| Palatability of meal | at 260 minutes | Measured by VAS questionnaire |
| Physical comfort | 0-240 min | Measured by VAS questionnaire at 13 time points, used to calculate area under curve (AUC) (Composite measure) |
Countries
Canada
Outcome results
None listed