Diabetes Prevention, Obesity Prevention
Conditions
Brief summary
The objectives are to test the acute effects of different extruded pulse snacks on: 1) post-prandial blood glucose, insulin and appetite for two hours, and 2) food intake two hours following consumption of pulse products. The investigators hypothesize that snack products containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake responses compared to non-pulse snack products.
Interventions
OTHERControl
Non pulse extruded snack
Pulse extruded snack
Pulse extruded snack
OTHERLentil flour
Pulse extruded snack
OTHERNavy bean flour
Pulse extruded snack
OTHERPinto bean flour
Pulse extruded snack
Sponsors
Saskatchewan Pulse Growers
Alberta Pulse Growers
University of Manitoba
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Normoglycemic (\<5.6 mmol/L) and normotensive (systolic blood pressure \<140 mm Hg and diastolic blood pressure below \< 90 mm Hg) * BMI of 18.5-29.9 kg/m2
Exclusion criteria
* Restrained eaters * Regularly skip breakfast * Smokers * Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year * Competitive sports or athletic training at a high intensity * Those unable to walk for an hour continuously
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma Glucose and Insulin Concentrations | 0 - 200 min | Measured in blood using intravenous catheter at 12 time points and used to calculate area under curve (AUC). Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits (Composite measure) |
| Food Intake | at 120 min | Ad-libitum meal |
| Subjective Appetite | 0-200 min | Measured by VAS questionnaire at 12 time points used to calculate area under curve (AUC) (Composite measure) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Palatability of treatments | at 5 minutes | Measured by VAS questionnaire |
| Physical Comfort | 0-200 min | Measured by VAS questionnaire at 12 time points used to calculate area under curve (AUC). (Composite measure) |
| Palatability of meal | at 140 minutes | Measured by VAS questionnaire |
| Energy and Fatigue | 0-200 min | Measured by VAS questionnaire at 12 time points and use to calculate AUC. (Composite measure) |
Countries
Canada
Outcome results
None listed